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At lower, sub-anesthetic doses, it is a promising agent for treatment of pain and treatment-resistant depression. [22] As with many antidepressants, the results of a single administration wane with time. [23] Ketamine is used as a recreational drug for its hallucinogenic and dissociative effects. [24]
MDMA was also found to have effects on blood sugar levels comparable to high doses of ephedrine. Oberlin concluded that the effects of MDMA were not limited to the sympathetic nervous system. Research was stopped "particularly due to a strong price increase of safrylmethylamine", which was still used as an intermediate in methylhydrastinine ...
The International Association for the Study of Pain (IASP) defines chronic pain as a general pain without biological value that sometimes continues even after the healing of the affected area; [8] [9] a type of pain that cannot be classified as acute pain [b] and lasts longer than expected to heal, or typically, pain that has been experienced on most days or daily for the past six months, is ...
This requires them to increase their drug dosage to maintain the benefit, and that in turn also increases the unwanted side effects. [78] Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70]
Cholestasis is a condition where the flow of bile from the liver to the duodenum is impaired. [1] The two basic distinctions are: [1] obstructive type of cholestasis, where there is a mechanical blockage in the duct system that can occur from a gallstone or malignancy, and
Thalidomide brought on changes in the way drugs are tested, what type of drugs are used during pregnancy, and increased the awareness of potential side effects of drugs. According to Canadian news magazine programme W5 , most, but not all, victims of thalidomide receive annual benefits as compensation from the Government of Canada .
Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is an autoimmune primary disorder of hemostasis characterized by a low platelet count in the absence of other causes.
Sadism (/ ˈ s eɪ d ɪ z əm /) and masochism (/ ˈ m æ s ə k ɪ z ə m /), known collectively as sadomasochism (/ ˌ s eɪ d oʊ ˈ m æ s ə k ɪ z ə m / SAY-doh-MASS-ə-kiz-əm) or S&M, [1] is the derivation of pleasure from acts of respectively inflicting or receiving pain or humiliation. [2]