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Onychomadesis has been linked to autoimmune diseases, [7] physical trauma, pharmacological side effects, and viral infections, [8] especially coxsackieviruses. [9] However, in certain cases, the cause remains unknown. Athletes, especially runners, may be more likely to experience toenail involvement. [10]
The median life expectancy is around 9 years, and the average life expectancy is 16.3 years. [ 1 ] The causes of death are attributed to respiratory complications in the late stage of the disease (e.g. pneumonia ), neurological complications (e.g. drug resistant epilepsy ), and cardiac events.
Some patients may have asymmetry of the brain, with one side being noticeably larger than the other. [citation needed] One interesting phenomenon that seems very common in this syndrome is the tendency for disproportionate brain growth in the first few years of life, with crossing of percentiles on the head circumference growth charts.
Synucleinopathies (also called α-Synucleinopathies) are neurodegenerative diseases characterised by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells. [1] There are three main types of synucleinopathy: Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy ...
L1 syndrome is a group of mild to severe X-linked recessive disorders that share a common genetic basis. The spectrum of L1 syndrome disorders includes X-linked complicated corpus callosum dysgenesis, spastic paraplegia 1, MASA syndrome, and X-linked hydrocephalus with stenosis of the aqueduct of Sylvius (HSAS).
Life expectancy in the U.S. is projected to increase from 78.3 years in 2022 to 79.9 years in 2035 and to 80.4 years in 2050 for all sexes combined, researchers said.
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The disease has had no apparent effect on the twins' brains or personalities. Doctors do not know if the disease is fatal and, if so, what the life expectancy of one with this disease is. If the cause of the disease is genetic, there is a chance that the twins could pass it on to their future children. [7]