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  2. Heparin-induced thrombocytopenia - Wikipedia

    en.wikipedia.org/wiki/Heparin-induced...

    This results in platelet activation and the formation of platelet microparticles, which initiate the formation of blood clots; the platelet count falls as a result, leading to thrombocytopenia. [1] [7] In addition, the reticuloendothelial system (mostly the spleen) removes the antibody-coated platelets, further contributing to the thrombocytopenia.

  3. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...

  4. Immunoassay - Wikipedia

    en.wikipedia.org/wiki/Immunoassay

    In immunology the particular macromolecule bound by an antibody is referred to as an antigen and the area on an antigen to which the antibody binds is called an epitope. In some cases, an immunoassay may use an antigen to detect for the presence of antibodies, which recognize that antigen, in a solution.

  5. Helicase-dependent amplification - Wikipedia

    en.wikipedia.org/wiki/Helicase-dependent...

    The polymerase chain reaction is the most widely used method for in vitro DNA amplification for purposes of molecular biology and biomedical research. [1] This process involves the separation of the double-stranded DNA in high heat into single strands (the denaturation step, typically achieved at 95–97 °C), annealing of the primers to the single stranded DNA (the annealing step) and copying ...

  6. Test panel - Wikipedia

    en.wikipedia.org/wiki/Test_panel

    Another disadvantage is the fact that approximately 5% of the test results can be expected to fall outside the normal range for purely statistical reasons. Thus, there is an expectation that the number of abnormal appearing results will increase with the number of tests in the panel (for quantitative tests such as blood glucose and total protein).

  7. Blood compatibility testing - Wikipedia

    en.wikipedia.org/wiki/Blood_compatibility_testing

    Blood compatibility testing is routinely performed before a blood transfusion.The full compatibility testing process involves ABO and RhD (Rh factor) typing; screening for antibodies against other blood group systems; and crossmatching, which involves testing the recipient's blood plasma against the donor's red blood cells as a final check for incompatibility.

  8. Coombs test - Wikipedia

    en.wikipedia.org/wiki/Coombs_test

    [1] The direct Coombs test is used to test for autoimmune hemolytic anemia, a condition where the immune system breaks down red blood cells, leading to anemia. The direct Coombs test is used to detect antibodies or complement proteins attached to the surface of red blood cells. To perform the test, a blood sample is taken and the red blood ...

  9. Immunoradiometric assay - Wikipedia

    en.wikipedia.org/wiki/Immunoradiometric_assay

    However, only recently has the labeled antibody been applied to measurement of antigen to sample. The method converts the unknown antigen into a traceable radioactive product. Immunoradiometric assay (IRMA) was first introduced by "Miles and Hales" in 1968, who proposed certain theoretical advantages of the method with regard to improving the ...