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Diaminopimelic acid (DAP) is an amino acid, representing an epsilon-carboxy derivative of lysine. meso -α,ε-Diaminopimelic acid is the last intermediate in the biosynthesis of lysine and undergoes decarboxylation by diaminopimelate decarboxylase to give the final product.
2,6-DAP was used to treat leukemia since as early as 1951. [13] It is known to arrest progression of cell cycle in mouse leukemia cells by 1989. [ 14 ] Cancer cells are known to become resistant to DAP by losing their adenine phosphoribosyltransferase (APRT) function, [ 15 ] a process shared with E. coli .
DAP (gene), human gene that encodes death-associated proteins, which mediate programmed cell death Diamidophosphate, phosphorylating compound; Diaminopimelic acid, amino acid derivative of lysine
[4] [5] The redox reactions of nicotinamide adenine dinucleotide. The compound accepts or donates the equivalent of H −. [6] Such reactions (summarized in formula below) involve the removal of two hydrogen atoms from the reactant (R), in the form of a hydride ion (H −), and a proton (H +).
MurNAc is covalently linked to N-acetylglucosamine and may also be linked through the hydroxyl on carbon number 4 to the carbon of L-alanine. A pentapeptide composed of L-alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine is added to the MurNAc in the process of making the peptidoglycan strands of the cell wall.
Nested association mapping (NAM) is a technique designed by the labs of Edward Buckler, James Holland, and Michael McMullen for identifying and dissecting the genetic architecture of complex traits in corn .
The SAT Subject Test in Biology was the name of a one-hour multiple choice test given on biology by the College Board. A student chose whether to take the test depending upon college entrance requirements for the schools in which the student is planning to apply. Until 1994, the SAT Subject Tests were known as Achievement Tests; and from 1995 ...
Structural biology deals with structural analysis of living material (formed, composed of, and/or maintained and refined by living cells) at every level of organization. [ 1 ] Early structural biologists throughout the 19th and early 20th centuries were primarily only able to study structures to the limit of the naked eye's visual acuity and ...