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  2. File:Lac operon.pdf - Wikipedia

    en.wikipedia.org/wiki/File:Lac_operon.pdf

    You are free: to share – to copy, distribute and transmit the work; to remix – to adapt the work; Under the following conditions: attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made.

  3. lac operon - Wikipedia

    en.wikipedia.org/wiki/Lac_operon

    The lactose operon (lac operon) is an operon required for the transport and metabolism of lactose in E. coli and many other enteric bacteria.Although glucose is the preferred carbon source for most enteric bacteria, the lac operon allows for the effective digestion of lactose when glucose is not available through the activity of β-galactosidase. [1]

  4. Lactose permease - Wikipedia

    en.wikipedia.org/wiki/Lactose_permease

    The mechanism known as the "six-state" pertains to the six distinct functional conformations or states involved in the cotransport process of the lactose permease cotransporter. In state 1 the LacY protein, adopts an outward-facing conformation. Subsequently, through rapid binding of a hydrogen ion, it transitions to state 2.

  5. Beta-galactoside permease - Wikipedia

    en.wikipedia.org/wiki/Beta-galactoside_permease

    Galactoside permease is a protein coded by the lacY gene of the lac operon, and is found bound to the membrane of a cell for the purpose of binding galactoside molecules that have been solubilized. The protein is part of a system whose main function is to catalyze the accumulation and transport of lactose and other beta-galactosides across the ...

  6. Repressor - Wikipedia

    en.wikipedia.org/wiki/Repressor

    The lac operon: 1: RNA Polymerase, 2: lac repressor, 3: Promoter, 4: Operator, 5: Lactose, 6: lacZ, 7: lacY, 8: lacA. Top: The gene is essentially turned off.There is no lactose to inhibit the repressor, so the repressor binds to the operator, which obstructs the RNA polymerase from binding to the promoter and making lactase.

  7. SOS response - Wikipedia

    en.wikipedia.org/wiki/SOS_response

    As well as genetic resistance the SOS response can also promote phenotypic resistance. Here, the genome is preserved whilst other non-genetic factors are altered to enable the bacteria to survive. The SOS dependent tisB-istR toxin-antitoxin system has, for example, been linked to DNA damage-dependent persister cell induction. [12]

  8. Silencer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Silencer_(genetics)

    The lac operon in the prokaryote E. coli consists of genes that produce enzymes to break down lactose. Its operon is an example of a prokaryotic silencer. The three functional genes in this operon are lacZ, lacY, and lacA. [6] The repressor gene, lacI, will produce the repressor protein LacI which is under allosteric regulation.

  9. Expression vector - Wikipedia

    en.wikipedia.org/wiki/Expression_vector

    [8] [9] [10] The promoters used for these vector are usually based on the promoter of the lac operon or the T7 promoter, [11] and they are normally regulated by the lac operator. These promoters may also be hybrids of different promoters, for example, the Tac-Promoter is a hybrid of trp and lac promoters. [12]