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The insufflation of cocaine crystals may also cause physical trauma to epithelial cells, leading to inflammatory lesions, which may also worsen due to the tendency for patients to physically remove the scabs produced in the damaged tissue, which induces further mechanical damage. [6] Cocaine is capable of inducing apoptosis of epithelial cells ...
Levamisole has become a common additive to illicit cocaine. It is thought to intensify the "high" by releasing dopamine in the brain, acts as a bulking agent, and is a difficult adulterant to recognize. Potential risks of levamisole-laced cocaine include neutropenia, agranulocytosis, arthralgias, retiform purpura, skin necrosis, and fever.
Any damage to the inside of the nose is due to cocaine constricting blood vessels — and therefore restricting blood and oxygen/nutrient flow — to that area. Rolled up banknotes, hollowed-out pens, cut straws, pointed ends of keys, specialized spoons, [57] long fingernails, and (clean) tampon applicators are often used to insufflate cocaine.
Troubled comedian Artie Lange, 51, revealed he would be attending rehab after testing positive for multiple drugs, including cocaine, while serving his four-year probation for heroin possession.
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A nasal septum perforation is a medical condition in which the nasal septum, the bony/cartilaginous wall dividing the nasal cavities, develops a hole or fissure. [1]This may be brought on directly, as in the case of nasal piercings, or indirectly, as by long-term topical drug application, including nasal administration of ethylphenidate, methamphetamine, cocaine, crushed prescription pills, or ...
The strip will change color or show a line if the liquid tests positive for fentanyl. Anyone who is a regular user of hard drugs - not just heroin or opioids - should keep naloxone on hand in case ...
Cocaine is associated with retinal toxicity mainly through its negative impacts on the retinal vasculature. [18] Cocaine use causes increased norepinephrine levels and the resulting sympathetic activation leads to vasospasm and hypertension, [ 19 ] both of which are risk factors to retinal blood vessel damage.