Search results
Results from the WOW.Com Content Network
Axon terminals (also called terminal boutons, synaptic boutons, end-feet, or presynaptic terminals) are distal terminations of the branches of an axon. An axon, also called a nerve fiber, is a long, slender projection of a nerve cell that conducts electrical impulses called action potentials away from the neuron's cell body to transmit those ...
The presynaptic axon terminal, or synaptic bouton, is a specialized area within the axon of the presynaptic cell that contains neurotransmitters enclosed in small membrane-bound spheres called synaptic vesicles (as well as a number of other supporting structures and organelles, such as mitochondria and endoplasmic reticulum).
A diagram of the proteins found in the active zone. The active zone is present in all chemical synapses examined so far and is present in all animal species. The active zones examined so far have at least two features in common, they all have protein dense material that project from the membrane and tethers synaptic vesicles close to the membrane and they have long filamentous projections ...
Endocannabinoids, synthesized in and released from postsynaptic neuronal elements and their cognate receptors, including the (GPCR) CB1 receptor located at the presynaptic terminal, are involved in this modulation by a retrograde signaling process, in which these compounds are synthesized in and released from postsynaptic neuronal elements and ...
This difference across the membrane is what the neuron uses to actually do the work of sending messages from the axon hillock of the neuron all the way down to the presynaptic terminal and then on to the postsynaptic terminal because of the release of neurotransmitter into the synaptic cleft. [3]
PTPs are thought to result primarily from the buildup of calcium concentration in the axon terminal of the presynaptic neuron during the stimulus train. [2] However, this is a topic under debate [ 3 ] as changes that last this long outlive the rate at which calcium is transported out of the presynaptic neuron.
within the presynaptic terminal when action potentials propagate close together in time. [4] Facilitation of excitatory post-synaptic current (EPSC) can be quantified as a ratio of subsequent EPSC strengths. Each EPSC is triggered by pre-synaptic calcium concentrations and can be approximated by: EPSC = k([Ca 2+] presynaptic) 4 = k([Ca 2+] rest ...
Calcium ion signaling to the axon terminal is the usual signal for presynaptic release of neurotransmitters. Calcium ion diffusion into the presynaptic membrane signals the axon terminal to release quanta to generate either an IPSP or EPSP in the postsynaptic membrane. Release of different neurotransmitters will lead to different postsynaptic ...