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The role for these products is between just the use of simple analgesics (paracetamol or ibuprofen) and the triptan class of drugs; although the latter are not options during pregnancy. [7] In the elderly although triptans are generally avoided, so too are antiemetics such as metoclopramide due to higher risks of side effects.
Paracetamol's bioavailability is dose-dependent: it increases from 63 % for 500 mg dose to 89 % for 1000 mg dose. [6] Its plasma terminal elimination half-life is 1.9–2.5 hours, [ 6 ] and volume of distribution is roughly 50 L. [ 132 ] Protein binding is negligible, except under the conditions of overdose, when it may reach 15–21 %. [ 6 ]
Panadol Rapid Handipak is Panadol Rapid packaged in a slim container of ten 500 mg caplets, designed to appeal to Australian women who are 20 to 35 years of age. [24] [25] Panadol Cold and Catarrh contains three active ingredients: paracetamol, phenylephrine hydrochloride as a nasal decongestant, and chlorpheniramine maleate to prevent certain ...
The active ingredient of its original flagship product is paracetamol (known in the United States, Canada, and various other countries as acetaminophen), an analgesic and antipyretic. Like the words paracetamol and acetaminophen, the brand name Tylenol is derived from a chemical name for the compound, N-acetyl-para-aminophenol (APAP). [1]
Panadol night is a GlaxoSmithKline painkiller intended for use at night. It consists of 500 milligrams of paracetamol, 25 milligrams of diphenhydramine hydrochloride (a sedating antihistamine) and other "non-hazardous ingredients" [1] It is sold in Australia, Cyprus, United Kingdom, Ireland, New Zealand and the Middle East.
N-acetylcysteine, also known as Acetylcysteine and NAC, is a medication that is used to treat paracetamol (acetaminophen) overdose and to loosen thick mucus in individuals with chronic bronchopulmonary disorders, such as pneumonia and bronchitis. [9] It has been used to treat lactobezoar in infants.
It is packaged as white, round, biconvex, uncoated tablets, with each tablet containing 30 mg of pseudoephedrine hydrochloride (PSE), 500 mg of paracetamol (acetaminophen) and 2 mg of chlorpheniramine maleate (CPM) as the active ingredients. [1]
Midol was originally sold in 1911 as a headache and toothache remedy that was considered safer because it did not use the narcotics typically used at the time. [1] It was then promoted as a cure for hiccups claiming it controlled spasms, and finally as a remedy for menstrual cramps and bloating.