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His group has clarified pathways governing lipid uptake, transport, and efflux, demonstrating their impact on the function of immune cells and metabolic tissues in both physiological and pathological conditions. [2] His h-index is 113, with over 240 research articles published and cited over 68,000 times. [3]
As of 2024, she is an emeritus professor at Scripps Research, and serves on the advisory boards of the La Jolla Institute for Immunology and the San Diego Biomedical Research Institute. [3] [4] Her research has focused on immune tolerance and autoimmunity, particularly type 1 diabetes, as well as the immune response to tumors.
Alfred I. Tauber (born 1947) is an American philosopher and historian of science, who, from 1993 to 2010, served as director of the Boston University Center for Philosophy and History of Science at Boston University.
Immune tolerance encompasses the range of physiological mechanisms by which the body reduces or eliminates an immune response to particular agents. It is used to describe the phenomenon underlying discrimination of self from non-self, suppressing allergic responses, allowing chronic infection instead of rejection and elimination, and preventing ...
His research is focused on understanding T cell activation and immune tolerance in autoimmunity and organ transplantation. In April 2016, he co-founded and served as the president and CEO of the Parker Institute for Cancer Immunotherapy,. [3] In 2019, he co-founded and is Chief Executive Officer and President of Sonoma Biotherapeutics. [4]
The Los Angeles County Harbor General Hospital began its affiliation with UCLA School of Medicine in 1951. Construction of the present eight-story hospital building was completed in late 1962 on the easterly portion of the grounds, at Carson Street and Vermont Avenue, replacing a number of the wooden barracks and cottages comprising Harbor ...
Matzinger is chief of the T-Cell Tolerance and Memory Section at the U.S. National Institute of Allergy and Infectious Diseases (NIAID). [6] The lab has been referred to as the "Ghost Lab" for Matzinger's choice to conduct the first nine months of her research alone with a focus on chaos theory.
Immune tolerance can be defined as the ability of the immune system to distinguish between self and non-self, or harmless and harmful. T-cells are able to distinguish between self and non-self largely through their T-cell receptor, or TCR. Immune tolerance is maintained by central and peripheral tolerance.