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Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8]It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them.
An ectoparasiticide is an antiparasitic drug used in the treatment of ectoparasitic infestations. [1] These drugs are used to kill the parasites that live on the body surface. Permethrin , sulfur , lindane , dicophane , benzyl benzoate , ivermectin and crotamiton are well known ectoparasiticides. [ 2 ]
Benzyl benzoate is an effective and inexpensive topical treatment for human scabies. [7] It has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs. [8] It is also used as an excipient in some testosterone-replacement medications (like Nebido) for treating hypogonadism. [9]
Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
In humans, cypermethrin is deactivated by enzymatic hydrolysis to several carboxylic acid metabolites, which are eliminated in the urine. Worker exposure to the chemical can be monitored by measurement of the urinary metabolites, while severe overdosage may be confirmed by quantitation of cypermethrin in blood or plasma.
Most of the adverse human health effects reported for lindane have been related to agricultural uses and chronic, occupational exposure of seed-treatment workers. [ 34 ] Exposure to large amounts of lindane can harm the nervous system , producing a range of symptoms from headache and dizziness to seizures, convulsions, and more rarely, death.
The condition can be passed from person to person through sexual or close skin-to-skin contact.
Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. [4] While it may be used during pregnancy, it is not recommended for use during breastfeeding. [4] Praziquantel is in the anthelmintic class of medications. [3] It works partly by affecting the function of the worm's sucker. [3]
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