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Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. [3] [4] It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. [3] It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. [1] [2]
Other treatments may include biofeedback or in rare cases surgery. [4] In the general population rates of constipation are 2–30 percent. [7] Among elderly people living in a care home the rate of constipation is 50–75 percent. [11] People in the United States spend more than US$250 million on medications for constipation a year. [14]
Lubiprostone, sold under the brand name Amitiza among others, is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. The drug is owned by Mallinckrodt and is marketed by Takeda Pharmaceutical Company.
Prucalopride, sold under brand names Resolor and Motegrity among others, is a medication acting as a selective, high affinity 5-HT 4 receptor agonist [4] which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements.
Chronic constipation may be a sign of irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD); a gastroenterologist can recommend both lifestyle changes and medications to help.
The first line of treatment for constipation before other options are explored is often diet. What foods help relieve constipation? There are many foods, most of which are high in fiber, that can ...
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