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Up to one-third of kratom users experience an adverse side effect, which may involve cardiac arrest, liver damage, brain bleeding, or seizures. In some cases, kratom use has resulted in overdose ...
"abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents" [3] Chaparral: creosote bush, gobernadora, larreastat [4] Larrea tridentata, Larrea divaricata [4] Liver damage, [3] [4] [5] kidney problems, [4] Hypotension in cancer patients [3] Chinese herbal mixtures: Heavy metal ...
And kratom addiction can cause major life problems in the same way other drug dependence does, Dr. David I. Deyhimy, founder and medical director of MYMATCLINIC and Pulse Addiction, tells Yahoo ...
In smaller doses, kratom can produce stimulant effects, according to the Centers for Disease Control and Prevention. If taken in higher doses, it can produce effects similar to opioids.
Kratom overdose is a subject of concern in many countries because of the associated rising number of hospitalizations and deaths in which chronic kratom use is a contributing factor. [11] [16] According to clinical reviews, a kratom overdose can cause liver toxicity, seizures, coma, and death, [16] especially in combination with excessive ...
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
The FDA tested 30 different kratom products in 2019 and found "significant levels" of lead and nickel in them, which researchers said could cause heavy metal poisoning if consumed over the long term.
Biological Toxins such as Diphtheria toxin [18]; Radiation Therapy is known to cause radiation-induced heart disease (RIHD) [19] These agents can lead to varying degrees of cardiotoxicity, and their effects may be dose-dependent and influenced by individual factors such as pre-existing cardiovascular disease and genetic predispositions that can foster greater sensitivity to any cardiac damage.