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TrimSpa was a dietary supplement designed for weight loss, marketed by the company Goen Technologies and headed by Alexander Szynalski. [1] The ephedra-based supplement was marketed by TrimSpa to help "stave off hunger", [2] until ephedra was banned from the United States. TrimSpa's parent company, Goen Technologies, filed for bankruptcy ...
Ephedra is widely used by athletes as a performance-enhancing drug, [13] despite a lack of evidence that it improves athletic performance. [14] [15] Ephedra may also be used as a precursor in the illicit manufacture of methamphetamine. [16] Ephedra has been used as a weight-loss aid, sometimes in combination with aspirin and caffeine.
In the United States, it is illegal to market products containing ephedrine or ephedra alkaloids as a dietary supplement. [1] In 2004, ephedra , a botanical source of ephedrine alkaloids, was banned by the U.S. Food and Drug Administration due to serious safety concerns, injuries, and deaths linked to ephedra-containing supplements.
Chemins was the manufacturer of dietary supplements for the multi-level marketing companies Metabolife (i.e., Metabolife 356, an ephedra-based supplement that was withdrawn following numerous adverse event reports) [4] [5] and LifeVantage (i.e., Protandim, an herbal-based supplement). [6] Chemins' assets were acquired by Nexgen Pharma in 2007. [7]
Metabolife's best-selling product, an ephedra supplement called Metabolife 356, once generated hundreds of millions of dollars in annual sales. [1] However, Metabolife 356 and other ephedra-containing supplements were linked to thousands of serious adverse events , including deaths, which caused the U.S. Food and Drug Administration (FDA) to ...
Ephedra is a genus of gymnosperm shrubs.The various species of Ephedra are widespread in many arid regions of the world, ranging across southwestern North America, southern Europe, northern Africa, southwest and central Asia, northern China, and western South America. [2]
Ephedrine, one of the most well-known selective NRAs.. A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine (noradrenaline) and epinephrine (adrenaline) from the pre-synaptic neuron into the synapse.
Ephedra may refer to: Ephedra (medicine), a medicinal preparation from the plant Ephedra sinica; Ephedra, genus of gymnosperm shrubs; See also. Ephedrine This ...