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Complex regional pain syndrome is uncommon, and its cause is not clearly understood. CRPS typically develops after an injury, surgery, heart attack, or stroke. [8] [12] Investigators estimate that 2–5% of those with peripheral nerve injury, [13] and 13–70% of those with hemiplegia (paralysis of one side of the body) [14] will develop CRPS.
Chronic visceral pain from persistent inflammation is pain caused by chronic inflammation of internal organs. This inflammation can be caused by noninfectious, infectious, or autoimmune mechanisms. [26] Chronic visceral pain from persistent inflammation in the head or neck region; Chronic visceral pain from persistent inflammation in the ...
It states, "Complex regional pain syndrome (CRPS), formerly reflex sympathetic dystrophy (RSD) or "causalgia",…" Thie "or" part is misleading in the extreme--it implies that RSD and causalgia are two names for the same thing.
The International Association for the Study of Pain (IASP) defines chronic pain as a general pain without biological value that sometimes continues even after the healing of the affected area; [8] [9] a type of pain that cannot be classified as acute pain [b] and lasts longer than expected to heal, or typically, pain that has been experienced on most days or daily for the past six months, is ...
Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...
Anterior cutaneous nerve entrapment syndrome (ACNES) is a nerve entrapment condition that causes chronic pain of the abdominal wall. [1] It occurs when nerve endings of the lower thoracic intercostal nerves (7–12) are 'entrapped' in abdominal muscles, causing a severe localized nerve (neuropathic) pain that is usually experienced at the front of the abdomen.
Acute inflammation of the lung (usually in response to pneumonia) does not cause pain unless the inflammation involves the parietal pleura, which does have pain-sensitive nerve endings. [15] Heat and redness are due to increased blood flow at body core temperature to the inflamed site.
This leads to the organ-specific damage typical of autoimmune disease. [19] Molecular mimicry may be particularly relevant to the tolerance breakdown linked to autoimmune neuropathies. The process known as " molecular mimicry " occurs when an infectious organism that shares epitopes from its host's afflicted tissue triggers an immune response ...