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Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
For example, slow dissolution rates can prolong the duration of action or avoid initial high plasma levels. Treatment of active ingredient by special ways such as spherical crystallization [ 2 ] can have some advantages for drug formulation.
A clinical chemistry analyzer; hand shows size. Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is a division in medical laboratory sciences focusing on qualitative tests of important compounds, referred to as analytes or markers, in bodily fluids and tissues using analytical techniques and specialized instruments. [1]
Download as PDF; Printable version; In other projects Wikimedia Commons; Wikidata item; ... Chemical substances for emergency medicine (2 C, 42 P) D. Drugs (34 C, 48 ...
Download as PDF; Printable version; ... move to sidebar hide. Help. Chemistry portal; Medicine portal Subcategories. This category has the following 8 subcategories ...
The structure–activity relationship (SAR) is the relationship between the chemical structure of a molecule and its biological activity.This idea was first presented by Alexander Crum Brown and Thomas Richard Fraser at least as early as 1868.
A particular example of rational drug design involves the use of three-dimensional information about biomolecules obtained from such techniques as X-ray crystallography and NMR spectroscopy. Computer-aided drug design in particular becomes much more tractable when there is a high-resolution structure of a target protein bound to a potent ligand.
Molecular oncology is an interdisciplinary medical specialty at the interface of medicinal chemistry and oncology that refers to the investigation of the chemistry of cancer and tumors at the molecular scale. Also the development and application of molecularly targeted therapies.