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Guanfacine Interactions. There are 477 drugs known to interact with guanfacine, along with 5 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 82 are major, 390 are moderate, and 5 are minor.
Guanfacine may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your physician or dentist.
Interactions. What is guanfacine? Guanfacine is used to treat high blood pressure (hypertension). It is sometimes given with other blood pressure medications. The Intuniv brand of guanfacine is used to treat attention deficit hyperactivity disorder (ADHD). Guanfacine may also be used for purposes not listed in this medication guide.
Speak to your doctor about how drug interactions should be managed. Common medications that may interact with guanfacine include: alcohol. antibiotics, such as ciprofloxacin, clarithromycin, erythromycin, fluconazole, or itraconazole. anticonvulsants, such as carbamazepine, phenytoin, or phenobarbital.
Guanfacine drug interactions range from mild to severe, depending on the other drug classifications. The medication also interacts with existing medical conditions, including depression, bradyarrhythmia (low resting heart rate), hypotension (low blood pressure) and renal disorders, among others.
Find patient medical information for guanfacine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Guanfacine has mild interactions with at least 46 different drugs. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use.
Guanfacine is a selective alpha-2A adrenergic receptor agonist, which reduces the effects of the sympathetic nervous system on the heart and circulatory system. 11 The link between guanfacine’s molecular mechanism and it’s effect on the treatment of ADHD has not been determined. 11
guanfacine increases levels of valproic acid by unknown mechanism. Use Caution/Monitor. Both 3-hydroxy guanfacine (metabolite) and valproic acid are metabolized by glucuronidation, possibly resulting in competitive inhibition. verapamil. verapamil will increase the level or effect of guanfacine by affecting hepatic/intestinal enzyme CYP3A4 ...
Guanfacine has the following interaction information: Drug interaction information. Severe interactions are highlighted with a red marker. Find out more about BNF interactions information. Guanfacine. 288 interactions. Acebutolol. Both Guanfacine and Acebutolol can increase the risk of hypotension. Agomelatine.