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OGT cleaves Host Cell Factor C1, at one or more of 6 repeating 26 amino acid sequences. The TPR domain of OGT binds to the carboxyl terminal portion of an HCF1 proteolytic repeat so that the cleavage region is in the glycosyltransferase active site above uridine-diphosphate-GlcNAc [11] The large proportion of OGT complexed with HCF1 is necessary for HCF1 cleavage, and HCFC1 is required for OGT ...
Ohio Graduation Test. The Ohio Graduation Test (OGT) is the high school graduation examination given to sophomores in the U.S. state of Ohio. Students must pass all five sections (reading, writing, mathematics, science and social studies) in order to graduate. Students have multiple chances to pass these sections and can still graduate without ...
O-GlcNAc (short for O-linked GlcNAc or O-linked β-N-acetylglucosamine) is a reversible enzymatic post-translational modification that is found on serine and threonine residues of nucleo cytoplasmic proteins. The modification is characterized by a β-glycosidic bond between the hydroxyl group of serine or threonine side chains and N ...
Two conserved enzymes control this glycosylation of serine and threonine: O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). While OGT catalyzes the addition of O-GlcNAc to serine and threonine, OGA catalyzes the hydrolytic cleavage of O-GlcNAc from post-transitionally modified proteins. [14] OGA is a member of the family of hexosaminidases ...
OGT may refer to: Ohio Graduation Test, a statewide exit test as a result of the No Child Left Behind Act. Original Gangster Tool, someone who claims to have been a fan of rock/metal band Tool since the beginning (from the time of the release of the Opiate EP in 1992); term appears in Tool's 1996 song "Hooker with a Penis".
Ohio Achievement Assessment. The Ohio Achievement Assessment (commonly stylized as the OAA) is a standardized test meeting NCLB requirements. Grades 3-8 are tested in reading, mathematics, science, social studies, and writing. [1] Before 2010, the Ohio Achievement Assessment was known as the Ohio Achievement Test. [2]
AGT II shows a greater preference for O4 -alkyl thymine than O6 -alkyl guanine and alkyl phosphotriester. [1] [2] Unlike Ada, AGT II is expressed constitutively in cells. [1] [3] Therefore, AGT II will repair alkylated DNA adducts even before Ada is fully induced. AGT II is similar to Ada in its suicide inactivation in that AGT II transfers the ...
Education portal. United States portal. v. t. e. The Ohio Department of Education and Workforce (DEW) is the administrative department of the Ohio state government [1] responsible for primary and secondary public education in the state. The Ohio State Board of Education is the governing body of the department and is responsible for overseeing ...