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Apalutamide was first described in 2007, and was approved for the treatment of prostate cancer in February 2018. [ 8 ] [ 9 ] [ 10 ] [ 15 ] It is the first medication to be approved specifically for the treatment of non-metastatic castration-resistant prostate cancer.
Side effects of vosilasarm in preliminary clinical studies in women with metastatic breast cancer have included vomiting (27%), dehydration (27%), constipation, decreased appetite and weight loss (27%), hypophosphatemia, decreased sex hormone-binding globulin (SHBG) levels (100%), increased prostate-specific antigen (PSA) levels (80%), and abnormal liver function tests, including elevated ...
In rat models of benign prostatic hyperplasia (BPH), a condition where the prostate is enlarged in the absence of prostate cancer, SARMs reduced the weight of the prostate. [66] OPK-88004 advanced to a phase II trial in humans, but it was terminated due to difficulty in measuring prostate size, the trial's primary endpoint. [19]
Darolutamide, sold under the brand name Nubeqa, is an antiandrogen medication which is used in the treatment of non-metastatic castration-resistant prostate cancer in men. [8] [4] [5] [9] [10] It is specifically approved to treat non-metastatic castration-resistant prostate cancer (nmCRPC) in conjunction with surgical or medical castration. [4]
Pumpkin Seeds. Pumpkin seeds can also help keep your prostate healthy. “Pumpkin seeds provide fiber, protein, magnesium, manganese, zinc, and healthy fat.Their high zinc content may be ...
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