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Referring to a common salt of fluoride, sodium fluoride (NaF), the lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride/kg body weight). [ 2 ] [ 3 ] [ 4 ] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 ...
Sodium fluoride (NaF) is an inorganic compound with the formula Na F. It is a colorless or white solid that is readily soluble in water. ... This page was last edited ...
Dr. Dean's research on the fluoride-dental caries relationship, published in 1942, included 7,000 children from 21 cities in Colorado, Illinois, Indiana, and Ohio. The study concluded that the optimal amount of fluoride which minimized the risk of severe fluorosis but had positive benefits for tooth decay was 1 mg per day, per adult.
But a fluoride level of above 1.5 mg/L is found in wells and community water systems that serve over 2.9 million people in the U.S., according to the study authors. Further, the study notes ...
For fluoride varnish treatment, the benefit to cost ratio 1.8:1, whereas fluoride mouth rinsing is 0.9:1. With fluoride varnish treatments, one can save by preventing future restorations. Fluoride varnish also requires fewer treatments for measurable effectiveness, therefore in the long run it is cost effective when compared to other treatments ...
Fluoride therapy typically uses the sodium fluoride form, though stannous fluoride may also be used. [4] [5] Fluoride decreases breakdown of teeth by acids, promotes remineralisation, and decreases the activity of bacteria. [5] Fluoride works primarily through direct contact with teeth. [3] [5] Fluoride came into use to prevent tooth decay in ...
Food, fluoride and funding: How a new Trump term might affect health in California Karen Kaplan, Corinne Purtill, Emily Alpert Reyes November 8, 2024 at 6:00 AM
[53] [54] [55] A case of a fatal poisoning of an adult with 4 grams of sodium fluoride is documented, [56] and a dose of 120 g sodium fluoride has been survived. [57] For sodium fluorosilicate (Na 2 SiF 6), the median lethal dose (LD 50) orally in rats is 125 mg/kg, corresponding to 12.5 g for a 100 kg adult. [58]
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