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In the 1800s, sugar coating and gelatin coating were invented, as were gelatin capsules. [1] In 1843, the British painter and inventor William Brockedon was granted a patent for a machine capable of "Shaping Pills, Lozenges, and Black Lead by Pressure in Dies". The device was capable of compressing powder into a tablet without the use of an ...
In ancient Greece, pills were known as katapotia ("something to be swallowed"). Pliny the Elder, who lived from 23–79 CE, first gave a name to what we now call pills, calling them pilula. [2] Pliny also wrote Naturalis Historia a collection of 38 books and the first pharmacopoea.
500 BC – Pills were used. They were presumably invented so that measured amounts of a medicinal substance could be delivered to a patient. 510–430 BC – Alcmaeon of Croton scientific anatomic dissections. He studied the optic nerves and the brain, arguing that the brain was the seat of the senses and intelligence.
According to Norman E. Himes, most methods of birth control used in antiquity were probably ineffective. [9] The single most effective method of birth control known in antiquity was probably coitus interruptus. [9] The ancient Greek philosopher Aristotle (c. 384–322 BC) recommended applying cedar oil to the womb before intercourse. [9]
Beecham's Pills were marketed primarily as a laxative from 1842. They were invented by Thomas Beecham from St Helens, Lancashire, England. The pills were a combination of aloe, ginger, and soap, with some other more minor ingredients. The popularity of the pills produced a wide range of testimonials that were used in advertising.
A 2007 report [57] found that of the 974 small molecule new chemical entities developed between 1981 and 2006, 63% were natural derived or semisynthetic derivatives of natural products. For certain therapy areas, such as antimicrobials, antineoplastics, antihypertensive and anti-inflammatory drugs, the numbers were higher. [citation needed]
[citation needed] For this reason, producers of drugs such as OTC analgesics wanting to emphasize the strength of their product developed the "caplet", a portmanteau of "capsule-shaped tablet", [1] to tie this positive association to more efficiently produced tablet pills, as well as being an easier-to-swallow shape than the usual disk-shaped ...
His Liber servitoris is of particular interest, as it provides the reader with recipes and explains how to prepare the "simples" from which were compounded the complex drugs then generally used. Shapur ibn Sahl (d. 869), was, however, the first physician to initiate a pharmacopoeia, describing a large variety of drugs and remedies for ailments.