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The process of spermatogenesis as the cells progress from primary spermatocytes, to secondary spermatocytes, to spermatids, to Sperm Cycle of the seminiferous epithelium of the testis. Spermatocytogenesis is the male form of gametocytogenesis and results in the formation of spermatocytes possessing half the normal complement of genetic material.
Most recently, the environmental effects on spermatogenesis have become a focus as male infertility in men has become more prevalent. [ 17 ] An important discovery in the spermatogenesis process was the identification of the seminiferous epithelial cycle in mammals—work by C.P. Leblound and Y. Clermont in 1952 that studied the spermatogonia ...
Spermatogenesis, the process for producing spermatozoa, takes place in the seminiferous tubules. During spermatogenesis, the DNA of spermatogenic cells in the seminiferous tubules is subject to damage from such sources as reactive oxygen species. [1] The genomic integrity of spermatogenic cells is protected by DNA repair processes. [2]
Irradiation of male mice during late spermatogenesis can induce damage that persists for at least 7 days in the fertilizing sperm cells, and disruption of maternal DNA double-strand break repair pathways increases sperm cell-derived chromosomal aberrations. [21]
Male gonad (testes, left) and female gonad (ovaries, right) Males have two testicles of similar size contained within the scrotum, which is an extension of the abdominal wall. [1] Scrotal asymmetry, in which one testicle extends farther down into the scrotum than the other, is common. This is because of the differences in the vasculature's ...
Spermatogenesis is the process in which sperm cells are produced and formed into mature spermatozoa from spermatogonia. Males mature spermatozoa (sperm) are produced to later join with a female oocyte (egg) to create offspring. Throughout the process of spermatogenesis, there are many different parts of the male anatomy, accessory organs, and ...
Because its main function is to nourish developing sperm cells through the stages of spermatogenesis, the Sertoli cell has also been called the "mother" or "nurse" cell. [10] Sertoli cells also act as phagocytes, consuming the residual cytoplasm during spermatogenesis. Translocation of cells from the basal lamina to the lumen of the ...
Spermatocytogenesis is the male form of gametocytogenesis and involves stem cells dividing to replace themselves and to produce a population of cells destined to become mature sperm. The stem cells involved are called spermatogonia and are a specific type of stem cell known as gametogonia.