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Since the 2010s, oxybutynin has increasingly been used to treat hyperhidrosis (excessive sweating). [15] [16] Numerous studies have identified concrete benefits of the drug in treating this condition, but have not identified appropriate dosing or the full spectrum of possible side effects, although dry mouth is seemingly infrequent in patients with hyperhidrosis.
Sofpironium bromide, sold under the brand name Ecclock among others, is a medication used to treat hyperhidrosis (excessive sweating). [1] Sofpironium bromide is an anticholinergic agent that is applied to the skin. [1] It was approved in Japan in 2020, for the treatment of primary axillary hyperhidrosis. [2]
These include excessive sweating, confusion, dizziness, or headaches. “[S]eek medical attention if symptoms appear,” Sylejmani advised. Consult with your doctor about adjusting your medication.
Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system. [ 1 ] [ 2 ] These agents inhibit the parasympathetic nervous system by selectively blocking the binding of ACh to its receptor in nerve cells .
Cyproheptadine is sometimes used off-label to improve akathisia in people on antipsychotic medications. [12] It is used off-label to treat various dermatological conditions, including psychogenic itch, [13] drug-induced hyperhidrosis (excessive sweating), [14] and prevention of blister formation for some people with epidermolysis bullosa ...
Glycopyrronium bromide is a medication of the muscarinic anticholinergic group. [7] It does not cross the blood–brain barrier and consequently has few to no central effects. It is given by mouth, [8] via intravenous injection, on the skin, [9] and via inhalation. [4] [5] [6] It is a synthetic quaternary ammonium compound. [2]
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