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Aluminum chloride hexahydrate, sold under the brand name Hydrosal Gel among others, is a first-line treatment for excessive sweating. [ 1 ] Clinical studies support the efficacy and low incidence of irritation of the 15% aluminum chloride and 2% salicylic acid gel base formula.
Aluminium chloride, also known as aluminium trichloride, is an inorganic compound with the formula AlCl 3. It forms a hexahydrate with the formula [Al(H 2 O) 6 ]Cl 3 , containing six water molecules of hydration .
For palmoplantar hyperhidrosis, 20% aluminum chloride hexahydrate in absolute anhydrous ethyl alcohol () is the most effective topical treatment. [4] Other topical treatments such as potassium permanganate, tannic acid (2 to 5 percent solutions), resorcinol, boric acid, formaldehyde, methenamine, and glutaraldehyde have yielded less than desirable results.
For severe cases of plantar and palmar hyperhidrosis, there has been some success with conservative measures such as higher strength aluminium chloride antiperspirants. [16] Treatment algorithms for hyperhidrosis recommend topical antiperspirants as the first line of therapy for hyperhidrosis. The International Hyperhidrosis Society has ...
The Canadian Hyperhidrosis Advisory Committee has published a comprehensive set of guidelines which outlines key aspects of treatment related to this condition. Topical hyperhidrosis gels containing aluminum chloride hexahydrate are usually first choice treatments for this condition. [3]
Cyanogen Chloride Gas: colorless Odor: pungent, irritating Seconds to minutes Headache, weakness, eye, nose and throat irritation, nausea, vomiting, and gasping for air Hydrogen chloride Gas: colorless, yellowish, or white Odor: strong, irritating Seconds to minutes Low does: eye and skin irritant High dose: rapid breathing, bluish
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