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Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis, cholestasis of pregnancy, jaundice of pregnancy, and prurigo gravidarum, [1] is a medical condition in which cholestasis occurs during pregnancy. [2] It typically presents with itching and can lead to complications for both mother and fetus. [2]
Pregnancy Symptoms Week 1. It's a bit of a mind-bender, but you aren't actually pregnant during what doctors call "week one" of pregnancy. Instead, week one starts on the first day of your last ...
For infants with hemolytic jaundice, severe and prolonged cases of hyperbilirubinemia, or high serum bilirubin that does not decrease after phototherapy, blood exchange transfusion is carried out at the umbilical venous catheter to mechanically remove bilirubin. [38] [39] [40] In cases of immune hemolytic jaundice, intravenous immunoglobulin ...
High at birth or rapidly rising bilirubin [3] Prolonged hyperbilirubinemia [3] Bilirubin-induced neurological dysfunction [4] Cerebral palsy [5] Kernicterus [6] [7] [8] Thrombocytopenia [7] Hemolytic anemia – must not be treated with iron [9] Late onset anemia – must not be treated with iron. Can persist up to 12 weeks after birth. [10] [11]
Emergency delivery due to failed IUT is possible, along with induction of labor at 35–38 weeks. [38] [41] Rhesus-negative mothers who are pregnant with a rhesus-positive infant are offered Rho(D) immune globulin (RhIG, or RhoGam) at 28 weeks during pregnancy, at 34 weeks, and within 48 hours after delivery to prevent sensitization to the D ...
[2] [1] A bilirubin level more than 34 μmol/L (2 mg/dL) may be visible. [1] Concerns, in otherwise healthy babies, occur when levels are greater than 308 μmol/L (18 mg/dL), jaundice is noticed in the first day of life, there is a rapid rise in levels, jaundice lasts more than two weeks, or the baby appears unwell. [1]
Typically the pain only lasts for a few seconds. During pregnancy, the growing uterus can put stress on the round ligament of the uterus, causing it to stretch and lead to pain. Paracetamol (acetaminophen) is the recommended pain reliever for pregnant women with round ligament pain.
If the bilirubin level is sufficiently high as to cause worry, it can be lowered via phototherapy in the first instance or an exchange transfusion if severely elevated. [citation needed] Phototherapy - Phototherapy is used for cord bilirubin of 3 or higher. Some doctors use it at lower levels while awaiting lab results. [19]
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