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  2. Biological therapy for inflammatory bowel disease - Wikipedia

    en.wikipedia.org/wiki/Biological_therapy_for...

    The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel disease Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [ 1 ]

  3. Budesonide - Wikipedia

    en.wikipedia.org/wiki/Budesonide

    [49] [50] When nebulized, budesonide has an bioavailability of 6% and reaches C max within 1–3 hours. [50] [49] When formulated as a rectal foam, budesonide has an bioavailability of 3% to 27% and reaches C max around 1.5 hours. [51] The plasma protein binding of budesonide is around 85-90%, with an apparent volume of distribution of 2.2-3.9L/kg.

  4. Inflammatory bowel disease - Wikipedia

    en.wikipedia.org/wiki/Inflammatory_bowel_disease

    Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...

  5. Ulcerative colitis - Wikipedia

    en.wikipedia.org/wiki/Ulcerative_colitis

    Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. [1] It is a long-term condition that results in inflammation and ulcers of the colon and rectum. [1] [7] The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). [1]

  6. Management of Crohn's disease - Wikipedia

    en.wikipedia.org/wiki/Management_of_Crohn's_disease

    Budesonide is released in the ileum and right colon, and therefore has a topical effect against disease in that area. [6] Steroid enemas can also be used to treat symptoms in the lower colon and rectum. Hydrocortisone and budesonide liquid and foam enemas are marketed for this purpose. [citation needed]

  7. Brawl ensues after Michigan deals stunning upset loss to ...

    www.aol.com/brawl-ensues-michigan-deals-stunning...

    An ugly brawl after the final whistle marred Michigan’s shocking upset win over rival Ohio State, who entered the game at the No. 2 team in the nation.

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