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S.M., sometimes referred to as SM-046, is an American woman with a peculiar type of brain damage that physiologically reduces her ability to feel fear.First described by scientists in 1994, [1] she has had exclusive and complete bilateral amygdala destruction since late childhood as a consequence of Urbach–Wiethe disease.
Urbach–Wiethe disease is inherited in an autosomal recessive manner. Urbach–Wiethe disease is a very rare recessive genetic disorder, with approximately 400 reported cases since its discovery. [1] [2] [3] It was first officially reported in 1929 by Erich Urbach and Camillo Wiethe, [4] [5] although cases may be recognized dating back as ...
Forest Park is a public park in western St. Louis, Missouri.It is a prominent civic center and covers 1,326 acres (5.37 km 2). [1] Opened in 1876, more than a decade after its proposal, the park has hosted several significant events, including the Louisiana Purchase Exposition of 1904 and the 1904 Summer Olympics.
Firmin Desloge plaque. In February 1930, Saint Louis University received a $1 million bequest ($18,239,044 today [3]) from the estate of Firmin Vincent Desloge, [4] a member of the Desloge Family in America, who provided in his will, funds for a hospital to serve St. Louis University and to replace the old St. Mary's Hospital, both in St. Louis. [5]
The university's 169-acre Danforth Campus is bordered by the Forest Park section of St. Louis and Clayton and University City, Missouri. View of Danforth Campus. A large portion of the Danforth Campus is recognized as the Washington University Hilltop Campus Historic District, which achieved National Historic Landmark status on February 27 ...
The park was named after Father Pere Marquette in 1915 [6] and covers 17 acres (6.9 ha). [6] Father Pere Marquette (a Jesuit priest) and Louis Jolliet were the first Europeans to explore and map the northern portion of the Mississippi River. [6] The park is on the site of the House of Refuge orphanage. [7]
The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history. “The bottom line is this is one of the very few health problems in this country that’s getting worse,” said Dr. Tom Frieden, director of the CDC.
DeMun is known as one of the most historically significant neighborhoods in St. Louis, “chock-full of 1920s architecture and peaceful, tree-lined streets.” [2] The neighborhood's residents are a mix of families, young professionals, and students — typically graduate and professional students from nearby Washington University in St. Louis. [3]