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PEG 400 is strongly hydrophilic.The partition coefficient of PEG 400 between hexane and water is 0.000015 (log =), indicating that when PEG 400 is mixed with water and hexane, there are only 15 parts of PEG400 in the hexane layer per 1 million parts of PEG 400 in the water layer.
PEG has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes. [18] PEG is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy. [19] PEG has been used as a solvent for aryl thioether synthesis. [20]
Poloxamer 407 is a hydrophilic non-ionic surfactant of the more general class of copolymers known as poloxamers.Poloxamer 407 is a triblock copolymer consisting of a central hydrophobic block of polypropylene glycol flanked by two hydrophilic blocks of polyethylene glycol (PEG).
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
The U.S. Code of Federal Regulations allows no more than 0.2% of diethylene glycol in polyethylene glycol when the latter is used as a food additive. [11] In Australia, it is only allowed at less than 0.25% w/w of DEG as an impurity in polyethylene glycol (PEG), [12] even in toothpaste. [13]
The choice of the suitable functional group for the PEG derivative is based on the type of available reactive group on the molecule that will be coupled to the PEG. For proteins, typical reactive amino acids include lysine, cysteine, histidine, arginine, aspartic acid, glutamic acid, serine, threonine and tyrosine.
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Superabsorbent polymers are now commonly made from the polymerization of acrylic acid blended with sodium hydroxide in the presence of an initiator to form a poly-acrylic acid sodium salt (sometimes referred to as sodium polyacrylate). This polymer is the most common type of SAP made in the world today.