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  2. Pituitary pars intermedia dysfunction - Wikipedia

    en.wikipedia.org/wiki/Pituitary_pars_intermedia...

    In PPID-affected horses, dopamine is not produced from these neurons, leading to dopamine levels about 10% of the level normally found in the pars intermedia. [2] This is thought to be due to neurodegeneration of the neurons, secondary to free radical formation and oxidative stress. [3]

  3. Geriatric horse - Wikipedia

    en.wikipedia.org/wiki/Geriatric_horse

    Geriatric pony with a lot of white hair on its head. There are several unmistakable signs that indicate a horse may be geriatric. Historically, determining a horse's age through observation was crucial, especially during a time when horses played a vital role in daily life For example, Le Nouveau Parfait Maréchal (18th century) advised observing specific features such as the teeth, tail ...

  4. Equine polysaccharide storage myopathy - Wikipedia

    en.wikipedia.org/wiki/Equine_polysaccharide...

    Equine polysaccharide storage myopathy (EPSM, PSSM, EPSSM) is a hereditary glycogen storage disease of horses that causes exertional rhabdomyolysis.It is currently known to affect the following breeds American Quarter Horses, American Paint Horses, Warmbloods, Cobs, Dales Ponies, Thoroughbreds, Arabians, New Forest ponies, and a large number of Heavy horse breeds.

  5. Cerebellar abiotrophy - Wikipedia

    en.wikipedia.org/wiki/Cerebellar_abiotrophy

    The symptoms, when taken as a group, are distinctive and not easily mimicked by other illnesses, though certain types of neurological injury and infection need to be ruled out. Verifying the diagnosis in a laboratory setting is possible only by examining the brain post-mortem to determine if there has been a loss of Purkinje cells. [5]

  6. Bartter syndrome - Wikipedia

    en.wikipedia.org/wiki/Bartter_syndrome

    Bartter syndrome (BS) is a rare inherited disease characterised by a defect in the thick ascending limb of the loop of Henle, which results in low potassium levels (hypokalemia), [2] increased blood pH (), and normal to low blood pressure.

  7. Proximal renal tubular acidosis - Wikipedia

    en.wikipedia.org/wiki/Proximal_renal_tubular...

    Patients with type 2 RTA are also typically hypokalemic due to a combination of secondary hyperaldosteronism, and potassium urinary losses - though serum potassium levels may be falsely elevated because of acidosis. Administration of bicarbonate prior to potassium supplementation might lead to worsened hypokalemia, as potassium shifts ...

  8. Equine exertional rhabdomyolysis - Wikipedia

    en.wikipedia.org/wiki/Equine_exertional...

    Adding potassium and salt to the diet may be beneficial to horses that suffer from recurrent bouts of ER both chronic and sporadic. Horses in hard training may need a vitamin E supplement, as their requirements are higher than horses in more moderate work. The horse may also be deficient in selenium, and need a feed in supplement.

  9. Gitelman syndrome - Wikipedia

    en.wikipedia.org/wiki/Gitelman_syndrome

    Gitelman syndrome; Other names: Primary renal tubular hypokalemic hypomagnesemia with hypocalciuria: A model of transport mechanisms in the distal convoluted tubule.Sodium chloride (NaCl) enters the cell via the apical thiazide-sensitive NCC and leaves the cell through the basolateral Cl − channel (ClC-Kb), and the Na + /K +-ATPase.