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Dutasteride is used for treating BPH, colloquially known as an "enlarged prostate". [9] [14] It is approved by the Food and Drug Administration (FDA) in the U.S. for this indication. [15] A 2010 Cochrane review found a 25–26% reduction in the risk of developing prostate cancer with 5α-reductase inhibitor chemoprevention. [16]
In addition, due to the relaxation of the prostate smooth muscle, another side effect that arises in men being treated for BPH is impotence, as well as the inability to ejaculate. [ 32 ] [ 34 ] However, if any ejaculation activity does occur, oftentimes, it results in a phenomenon called retrograde ejaculation , in which semen flows into the ...
A meta‐analysis found that tadalafil is an effective treatment for lower urinary tract symptoms due to benign prostatic hyperplasia and that such treatment had a low rate of adverse effects. [12] Tadalafil is FDA-approved for males as a therapy to treat and prevent symptoms of benign prostatic hyperplasia, such as urinary urgency, hesitancy ...
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