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Citalopram was approved for medical use in the United States in 1998. [7] It is on the World Health Organization's List of Essential Medicines. [11] It is available as a generic medication. [12] In 2022, it was the 40th most commonly prescribed medication in the United States, with more than 15 million prescriptions. [13] [14]
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
Paroxetine was the first drug to be approved for social anxiety disorder and it is considered effective for this disorder; sertraline and fluvoxamine were later approved for it as well. Escitalopram and citalopram are used off-label with acceptable efficacy, while fluoxetine is not considered to be effective for this disorder. [22]
Citalopram is taken after MDMA in the combination, and its inclusion is intended to help reduce the well-known negative after-effects of MDMA (sometimes referred to colloquially as "Blue Mondays"). [1] [4] [5] MDMA has been found to produce serotonin depletion and neurotoxicity in animals, and this may be importantly involved in its negative ...
Saphris – atypical antipsychotic used to treat schizophrenia and bipolar disorder; Serax – anti-anxiety medication of the benzodiazepine class, often used to help during detoxification from alcohol or other addictive substances; Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1]
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As of 2003, worldwide, 30% to 60% of people did not follow their practitioner's instructions about taking their antidepressants, [303] and as of 2013 in the US, it appeared that around 50% of people did not take their antidepressants as directed by their practitioner.
This is a list of investigational antidepressants, or drugs that are currently under development for clinical use in the treatment of depression but are not yet approved. Specific indications include major depressive disorder , treatment-resistant depression , dysthymia , bipolar depression , and postpartum depression , among others.