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  2. Myasthenia gravis - Wikipedia

    en.wikipedia.org/wiki/Myasthenia_gravis

    Myasthenia gravis most commonly occurs in women under the age of 40 and in men over the age of 60. [1] [5] [14] It is uncommon in children. [1] With treatment, most live to an average life expectancy. [1] The word is from the Greek mys, "muscle" and asthenia "weakness", and the Latin gravis, "serious". [15]

  3. Edrophonium - Wikipedia

    en.wikipedia.org/wiki/Edrophonium

    Lambert-Eaton myasthenic syndrome (LEMS), is similar to myasthenia gravis in that it is an autoimmune disease. However, in LEMS the neuron is unable to release enough acetylcholine for normal muscle function due to autoantibodies attacking P/Q-type calcium channel that are necessary for acetylcholine release.

  4. Amifampridine - Wikipedia

    en.wikipedia.org/wiki/Amifampridine

    Amifampridine phosphate is used as a drug, predominantly in the treatment of a number of rare muscle diseases. The free base form of the drug has been used to treat congenital myasthenic syndromes and approved by the FDA for Lambert–Eaton myasthenic syndrome (LEMS) through compassionate use programs since the 1990s and was recommended as a first line treatment for LEMS in 2006, using ad hoc ...

  5. Transient neonatal myasthenia gravis - Wikipedia

    en.wikipedia.org/wiki/Transient_neonatal...

    However, treatment with oral salbutamol, a drug that stimulates the beta-2 adrenergic receptor, [20] greatly reduced these symptoms within 48 hours. [31] In a subsequent study of 16 individuals with FARIS aged less than 4 weeks, 4 full weeks, 10 weeks, and 6 months to 17 years, oral salbutamol caused symptom improvements in 13 (81.3%) with all ...

  6. MDA Kickstart Program Receives FDA Rare Pediatric Disease ...

    lite.aol.com/tech/story/0022/20241024/9261747.htm

    "We’re proud to have made an impact with advocates for the reauthorization of the Rare Pediatric Disease PRV program as it is essential for continuing progress in rare disease treatment," said Paul Melmeyer, Executive Vice President of Public Policy and Advocacy, Muscular Dystrophy Association. "On September 10, an MDA contingent of more than ...

  7. Pyridostigmine - Wikipedia

    en.wikipedia.org/wiki/Pyridostigmine

    Pyridostigmine is an acetylcholinesterase inhibitor in the cholinergic family of medications. [3] It works by blocking the action of acetylcholinesterase and therefore increases the levels of acetylcholine. [3] Pyridostigmine was patented in 1945 and came into medical use in 1955. [4] It is on the World Health Organization's List of Essential ...

  8. New menopause drugs treat hot flashes, but women may face ...

    www.aol.com/news/menopause-drugs-treat-hot...

    New drugs to treat debilitating menopause symptoms — namely hot flashes — are finally on the market or are in development. But doctors say insurance companies either won’t pay for them or ...

  9. Neuromuscular-blocking drug - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular-blocking_drug

    The effect of non-depolarizing neuromuscular-blocking drugs may be reversed with acetylcholinesterase inhibitors, neostigmine, and edrophonium, as commonly used examples. Of these, edrophonium has a faster onset of action than neostigmine, but it is unreliable when used to antagonize deep neuromuscular block. [ 29 ]

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