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Febrile neutropenia or neutropenic fever is a defined as a single oral temperature value of ≥ 38.3 C (101 F) or a temperature ≥ 38 C (100.4 F) for ≥ 1 hour, with an absolute neutrophil count (ANC) < 1500 cell/microliter. [1]
Furthermore, emerging research suggests neutropenia without an identifiable etiology (idiopathic neutropenia) may be the result of a low-grade, chronic inflammatory process with an abnormal excessive production of myelosuppressive cytokines in a study conducted in the island of Crete. [33] Neutropenia fever can complicate the treatment of cancers.
Neutropenic enterocolitis, also known as typhlitis, is an inflammation of the cecum (part of the large intestine) that may be associated with infection. [1] It is particularly associated with neutropenia , a low level of neutrophil granulocytes (the most common form of white blood cells ) in the blood.
Fever of unknown origin (FUO) refers to a condition in which the patient has an elevated temperature for which no cause can be found despite investigations by one or more qualified physicians. [ 1 ] [ 2 ] [ 3 ] If the cause is found, it is usually a diagnosis of exclusion , eliminating all possibilities until only the correct explanation remains.
The treatment of established or suspected infection following exposure to radiation (characterized by neutropenia and fever) is similar to the one used for other febrile neutropenic patients. However, important differences between the two conditions exist.
Ceftazidime is the first-line treatment for the tropical infection, melioidosis, an important cause of sepsis in Asia and Australia. [11] [12] Labeled indications include the treatment of patients with: Pseudomonas aeruginosa infections; other Gram-negative, aerobic infections; neutropenic fever [13]
A major challenge in treating FS is recurring infection caused by neutropenia. Therefore, in order to decide upon and begin treatment, the cause and relationship of neutropenia with the overall condition must be well understood. [9] Most of the traditional medications used to treat RA have been used in the treatment of Felty's syndrome.
Autoimmune neutropenia (AIN) is a form of neutropenia which is most common in infants and young children [1] where the body identifies the neutrophils as enemies and makes antibodies to destroy them. Primary autoimmune neutropenia, another name for autoimmune neutropenia, is an autoimmune disease first reported in 1975 that primarily occurs in ...