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The brush border morphology increases a cell's surface area, a trait which is especially useful in absorptive cells. Cells that absorb substances need a large surface area in contact with the substance to be efficient.
The proximal tubule is the segment of the nephron in kidneys which begins from the renal pole of the Bowman's capsule to the beginning of loop of Henle.At this location, the glomerular parietal epithelial cells (PECs) lining bowman’s capsule abruptly transition to proximal tubule epithelial cells (PTECs).
The human gastrointestinal (GI) tract is full of tuft cells for its entire length. These cells were located between the crypts and villi. On the basal pole of all cells was expressed DCLK1. They did not have the same morphology as was describe in animal studies but they showed an apical brush border the same thickness.
The brush border on the apical surface of the epithelial cells is covered with glycocalyx, which is composed of oligosaccharides attached to membrane glycoproteins and glycolipids. [ 7 ] TEM image of a thin section cut through an epithelial cell showing the luminal surface (apical end) of the cell packed with microvilli that make up the ...
Thousands of microvilli form a structure called the brush border that is found on the apical surface of some epithelial cells, such as the small intestines. (Microvilli should not be confused with intestinal villi, which are made of many cells. Each of these cells has many microvilli.)
Intestinal villi (sg.: villus) are small, finger-like projections that extend into the lumen of the small intestine.Each villus is approximately 0.5–1.6 mm in length (in humans), and has many microvilli projecting from the enterocytes of its epithelium which collectively form the striated or brush border.
The cells here may possess microvilli for maximizing the surface area for absorption, and these microvilli may form a brush border. Other cells may be ciliated to move mucus in the function of mucociliary clearance. Other ciliated cells are found in the fallopian tubes, the uterus and central canal of the spinal cord.
The nuclei are located closer along the basal side of the cell. [1] Absorptive columnar epithelium is characterized as having a striated border on its apical side, this border is made up of non-motile microvilli allowing for increase surface area for absorption. [1] These are known as non-ciliated columnar epithelium.