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Lomustine is an alkylating chemotherapy drug that is indicated by the FDA for the treatment of patients with brain tumors (primary and metastatic), following any necessary surgery and radiation, as well as for treatment of progressive Hodgkin’s lymphoma. [ 8 ] Lomustine is approved for the treatment of brain tumors, breast cancer, lung cancer ...
AOH1996 is an experimental anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for the treatment of solid tumors. [1][2][3][4] AOH1996 was created to target a post-translationally modified isoform of PCNA, termed caPCNA ...
Contents. Docetaxel. Docetaxel (DTX or DXL), sold under the brand name Taxotere among others, is a chemotherapy medication used to treat a number of types of cancer. [ 6 ] This includes breast cancer, head and neck cancer, stomach cancer, prostate cancer and non-small-cell lung cancer. [ 7 ]
Gemcitabine is a chemotherapy drug that works by killing any cells that are dividing. [ 10 ] Cancer cells divide rapidly and so are targeted at higher rates by gemcitabine, but many essential cells also divide rapidly, including cells in skin, the scalp, the stomach lining, and bone marrow, resulting in adverse effects. [ 16 ]: 265.
Common side effects include low blood cell counts, fever, nausea, diarrhea, loss of appetite, cough, and rash. [3] Other severe side effects include allergic reactions and increased risk of infection. [3] Use in pregnancy is known to harm the baby. [3] Bendamustine is in the alkylating agents family of medication. [3]
The safety and effectiveness of trastuzumab emtansine were evaluated in a clinical study of 991 patients randomly assigned to receive trastuzumab emtansine or lapatinib plus capecitabine, another chemotherapy drug. [18] Patients received treatment until either the cancer progressed or the side effects became intolerable. [18]
Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. Their active moieties are coordination complexes of platinum. These drugs are used to treat almost half of people receiving chemotherapy for cancer. In this form of chemotherapy, commonly used drugs include cisplatin, oxaliplatin ...
Decitabine/cedazuridine, sold under the brand name Inqovi among others, is a fixed-dose combination anticancer medication used for the treatment of adults with myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML). [ 7 ][ 8 ][ 9 ] It is a combination of decitabine, a nucleoside metabolic inhibitor, and cedazuridine, a cytidine ...
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