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Molar mass. 145089.74 g·mol −1. Donanemab, sold under the brand name Kisunla, is a monoclonal antibody used for the treatment of Alzheimer's disease. [ 1 ][ 2 ] Donanemab was developed by Eli Lilly and Company. [ 3 ][ 4 ] The most common side effects include amyloid-related imaging abnormalities and headache.
Donanemab is a monoclonal antibody that binds to a protein that builds up in the brain during the early stages of Alzheimer’s. ... said that if a licensed treatment became available in the next ...
The Food and Drug Administration approved a new Alzheimer’s drug from Eli Lilly that has been shown in clinical trials to modestly slow a decline in memory and thinking abilities in people with ...
Lilly's donanemab was declined accelerated approval by the FDA in January 2023, and on March 8, the agency said it would hold a meeting of its advisers to discuss the drug, further delaying its ...
Donanemab was approved for medical use in the United States in July 2024 by the Food and Drug Administration. [32] Treatment is intended for patients with mild cognitive impairment or mild dementia stage of disease, which is the same population the treatment was studied in the clinical trials.
C6472H10028N1740O2014S46. Molar mass. 145912.34 g·mol −1. Aducanumab, sold under the brand name Aduhelm, is a monoclonal antibody designed to treat Alzheimer's disease. [ 2 ][ 3 ] It is a monoclonal antibody [ 3 ][ 2 ] that targets aggregated forms (plaque) [ 4 ][ 5 ] of amyloid beta (Aβ) found in the brains of people with Alzheimer's ...
The drug donanemab would be rejected by the National Institute for Health and Care Excellence (NICE), which decides what drugs are available on the NHS, the newspaper reported citing insiders. NHS ...
Solanezumab (proposed INN, LY2062430 [1]) is a monoclonal antibody being investigated by Eli Lilly as a neuroprotector [2] for patients with Alzheimer's disease. [3][4] The drug originally attracted extensive media coverage proclaiming it a breakthrough, but it has failed to show promise in Phase III trials. [5][6]