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Hydroxychloroquine and chloroquine have numerous, potentially serious, side effects, such as retinopathy, hypoglycemia, or life-threatening arrhythmia and cardiomyopathy. [26] Both drugs have extensive interactions with prescription drugs, affecting the therapeutic dose and disease mitigation. [26] [27] Some people have allergic reactions to ...
Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. [3]
Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [65] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [66] Neither drug has been useful to prevent or treat SARS-CoV-2 infection.
Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis , lupus , and porphyria cutanea tarda .
Combinations of DMARDs are often used, because each drug in the combination can be used in a smaller dose than if it were given alone, thus reducing the risk of side effects. [citation needed] Many patients receive an NSAID and at least one DMARD, sometimes with low-dose oral glucocorticoids. If disease remission is observed, regular NSAIDs or ...
Drug-drug interaction (DDI), an alteration of the action of a drug caused by the administration of other drugs; Paradoxical reaction, an effect of a substance opposite to what would usually be expected; Pharmacogenetics, the use of genetic information to determine which type of drugs will work best for a patient; Unintended consequences
Some prescription antidepressants, such as bupropion (Wellbutrin), are less likely to cause intimate side effects than others in the SSRI class of medications. Taking a temporary “drug holiday.”
Atovaquone/proguanil, sold under the brand name Malarone among others, is a fixed-dose combination medication used to treat and prevent malaria, including chloroquine-resistant malaria. [2] [3] It contains atovaquone and proguanil. [3] It is not recommended for severe or complicated malaria. [3] It is taken by mouth. [3]
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