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The work on this standard began in July 2002—subsequently, a U.S. Food and Drug Administration pilot project was initiated in July 2003 through a Cooperative Research and Development Agreement (CRADA). Feedback from this pilot and continuous efforts to more closely align this implementation with the SDTM for human clinical trials led to ...
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Chemical Research in Toxicology is a peer-reviewed scientific journal, published since 1988 by the American Chemical Society. [1] It is currently abstracted and indexed in Chemical Abstracts Service , Scopus , EBSCOhost , PubMed , CABI , Science Citation Index Expanded , and SwetsWise.
The threshold of toxilogical concern (or TTC) is a method for determining the level of exposure to chemicals above which would be considered toxic, [1] in cases where data about such chemicals is scarce or non-existent.
Such submission is a mandatory part of the registration process. Under certain circumstances the performance of a chemical safety assessment (CSA) is mandatory and a chemical safety report (CSR) assuring the safe use of the substance has to be submitted with the dossier. Dossier submission is done using the web-based software REACH-IT.
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Journal of Analytical Toxicology; Journal of Applied Toxicology; Journal of Environmental Science and Health, Part C; Journal of Exposure Science and Environmental Epidemiology; Journal of Immunotoxicology; Journal of Medical Toxicology; Journal of Toxicology and Environmental Health