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  2. Macrophage polarization - Wikipedia

    en.wikipedia.org/wiki/Macrophage_polarization

    Macrophage polarization is a process by which macrophages adopt different functional programs in response to the signals from their microenvironment. This ability is connected to their multiple roles in the organism: they are powerful effector cells of the innate immune system, but also important in removal of cellular debris, embryonic development and tissue repair.

  3. Tumor-associated macrophage - Wikipedia

    en.wikipedia.org/wiki/Tumor-associated_macrophage

    M1 macrophages are seen to have a pro-inflammatory and cytotoxic (anti-tumoral) function; M2 macrophages are anti-inflammatory (pro-tumoral) and promote wound healing. However, use of the M1/M2 polarization paradigm has led to confusing terminology since M1/M2 are used to describe mature macrophages, but the activation process is complex and ...

  4. Regulatory macrophages - Wikipedia

    en.wikipedia.org/wiki/Regulatory_macrophages

    Regulatory macrophages (Mregs) represent a subset of anti-inflammatory macrophages. In general, macrophages are a very dynamic and plastic cell type and can be divided into two main groups: classically activated macrophages (M1) and alternatively activated macrophages (M2). [1] M2 group can further be divided into sub-groups M2a, M2b, M2c, and ...

  5. Smoker's macrophages - Wikipedia

    en.wikipedia.org/wiki/Smoker's_macrophages

    A macrophage can be polarized into the classic M1 or M2 phenotype, and this phenomenon can be seen in cigarette consumption. [2] In this polarization scheme, lower M1 markers and higher M2 markers have been observed. [4] The reprogram of macrophage implies a dysregulated inflammation that can damage healthy lung cells.

  6. Macrophage-activating factor - Wikipedia

    en.wikipedia.org/wiki/Macrophage-activating_factor

    Macrophages have been classified as M1 or M2 depending on the adaptive immune response that elicited the phenotype: Th1 or Th2 respectively. [2] [4] [5] The phrase 'alternatively activated macrophage' is used to refer to M2 macrophages. [2] Regulatory macrophages do not fit into the M1/M2 classification system, and they display different ...

  7. Ham is the centerpiece of many holiday meals. Is it good for you?

    www.aol.com/ham-centerpiece-many-holiday-meals...

    High sodium diets may increase your risk of developing high blood pressure, cardiovascular disease, obesity, gastric cancer, osteoporosis, kidney disease and Meniere’s disease, per the WHO.

  8. Kupffer cell - Wikipedia

    en.wikipedia.org/wiki/Kupffer_cell

    M1 (classical activation) and M2 (alternative activation) designate the two extremes of macrophage polarization. M1-polarized Kupffer cells produce a large amount of pro-inflammatory cytokines like TNF-alpha. On the other hand, M2-polarized Kupffer cells produce a large quantity of anti-inflammatory mediators, for example, IL-10. [9] [4]

  9. Victims' lawyer questions timing of dementia diagnosis of ex ...

    www.aol.com/victims-lawyer-questions-timing...

    A lawyer for sex trafficking victims in a ring allegedly run by ex-Abercrombie & Fitch CEO Mike Jeffries has doubts about claims he has dementia.

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