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Those affected by schizophrenia are also more inclined to develop numerous physiological and psychological conditions. Most notably, they experience higher rates of substance abuse and suicidality; where more than half of people with schizophrenia have reported suicide ideation or attempts, and nearly half experience substance abuse or dependence. [19]
By using precise methods in its diagnosis and a large, representative population, schizophrenia seems to occur with relative consistency over time during the last half-century. [ 3 ] While it is claimed that schizophrenia occurs at similar rates worldwide, its prevalence and incidence varies across the world, [ 4 ] within countries, [ 5 ] and ...
Onset over the age of 60, which may be difficult to differentiate as schizophrenia, is known as very-late-onset schizophrenia-like psychosis. [55] Late onset has shown that a higher rate of females are affected; they have less severe symptoms and need lower doses of antipsychotics. [ 55 ]
Over the years, researchers had found that in people with schizophrenia, important parts of the brain are larger than usual, including the prefrontal cortex, which controls decision-making. Gray matter—the neural connections on which electrical signals travel, forming thoughts and emotions—is thinner.
Caffeine-induced psychosis is a relatively rare phenomenon that can occur in otherwise healthy people. Overuse of caffeine may also worsen psychosis in people suffering from schizophrenia. [1] It is characterized by psychotic symptoms such as delusions, paranoia, and hallucinations.
The management of schizophrenia usually involves many aspects including psychological, pharmacological, social, educational, and employment-related interventions directed to recovery, and reducing the impact of schizophrenia on quality of life, social functioning, and longevity.
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