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Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...
San Francisco Bay Area The San Francisco Bay Area , commonly known as the Bay Area, is a metropolitan region surrounding the San Francisco Bay estuaries in Northern California . According to the 2010 United States Census , the region has over 7.1 million inhabitants and approximately 6,900 square miles (18,000 km 2 ) of land. [ 1 ]
In the 1960s, San Francisco and surrounding Bay Area cities enacted strict zoning regulations. [53] Zoning is the legal restriction of parts of a city to particular uses, such as residential, industrial, or commercial. In San Francisco, it also includes limitations on building height, density, and shape, and banning the demolition of old buildings.
The San Francisco plague of 1900–1904 was an epidemic of bubonic plague centered on San Francisco 's Chinatown. It was the first plague epidemic in the continental United States. [ 1 ] The epidemic was recognized by medical authorities in March 1900, but its existence was denied for more than two years by California's Governor Henry Gage.
In 1967, the city of San Francisco, California, adopted Article 10 of the Planning Code, providing the city with the authority to designate and protect landmarks from inappropriate alterations. As of February 2019, the city has designated 288 structures or other properties as San Francisco Designated Landmarks. [1]
The Children's Creativity Museum is an interactive museum for children aged 2–12 years, located in Yerba Buena Gardens, in San Francisco, California. It offers workshops and exhibits that allow children to produce their own media through various interactive, creative processes: stop motion animation, programming robots, music video production ...
Cellulite caused by repetitive piercing of skin through intravenous injections. Scabs on the skin. Dark spots on the face and body. Serious tooth decay. Read more on the physical side effects of ...
1913. Closed. 1972. Area. 10 acres (40,000 m 2) Playland (also known as Playland-at-the-Beach and Whitney's Playland, beginning in 1928 [ 1] – some say 1926 [ 2]) was a 10-acre (40,000-square-meter) seaside amusement park located next to Ocean Beach, in the Richmond District at the western edge of San Francisco, California, along Great ...