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  2. Vitamin B12 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12

    Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.5–1.0 mg or more), [94] [95] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire ...

  3. Intrinsic factor - Wikipedia

    en.wikipedia.org/wiki/Intrinsic_factor

    Because vitamin B 12 absorption is a multistep process that involves the stomach, pancreas and small intestine, and is mediated by two carriers: Haptocorrin and intrinsic factor, and because Haptocorrin (transcobalamin I) binds to vitamin B 12, and Vitamin B 12 is acid-sensitive, when vitamin B 12 binds to Haptocorrin it can safely pass through ...

  4. Haptocorrin - Wikipedia

    en.wikipedia.org/wiki/Haptocorrin

    6947 n/a Ensembl ENSG00000134827 n/a UniProt P20061 n/a RefSeq (mRNA) NM_001062 n/a RefSeq (protein) NP_001053 n/a Location (UCSC) Chr 11: 59.85 – 59.87 Mb n/a PubMed search n/a Wikidata View/Edit Human Haptocorrin (HC) also known as transcobalamin-1 (TC-1) or cobalophilin is a transcobalamin protein that in humans is encoded by the TCN1 gene. One essential function of haptocorrin is ...

  5. The Top Signs You Have a Vitamin B12 Deficiency - AOL

    www.aol.com/top-sign-vitamin-b12-deficiency...

    How do you get tested for a B12 deficiency? ... your ability to absorb vitamin B12 may decline so I often recommend up to 1,000 mcg per day.” ... Adults need about 2.4 micrograms of B12 a day ...

  6. Transcobalamin - Wikipedia

    en.wikipedia.org/wiki/Transcobalamin

    TC-2 binds cobalamin once it has been taken up by enterocytes of the terminal ileum and the "Intrinsic Factor-Vitamin B12" complex has been degraded. TC-2 is then involved with the transport of Vitamin B12 to the tissues, where it binds to its plasma membrane receptor (TC-2R), a heavily glycosylated protein with a monomeric molecular mass of 62 ...

  7. Should You Get Vitamin B12 Injections? Here's ... - AOL

    www.aol.com/news/vitamin-b12-injections-heres...

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