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Medication administered via intramuscular injection is not subject to the first-pass metabolism effect which affects oral medications. Common sites for intramuscular injections include the deltoid muscle of the upper arm and the gluteal muscle of the buttock. In infants, the vastus lateralis muscle of the thigh is commonly used. The injection ...
They are provided as an oil solution and are administered by intramuscular injection. [5] The different testosterone esters provide for different elimination half-lives in the body. Esterification of testosterone provides for a sustained but non-linear release of testosterone hormone from the injection depot into the circulation. Sustanon 100 ...
20 mg testosterone propionate; 40 mg testosterone phenylpropionate; 40 mg testosterone isocaproate; They are provided as an oil solution and are administered by intramuscular injection. The different testosterone esters provide for different elimination half-lives in the body.
Testosterone propionate is administered in oil via intramuscular injection. [ 1 ] [ 2 ] It has a relatively short elimination half-life and mean residence time of 2 days and 4 days, respectively. [ 1 ] [ 2 ] As such, it has a short duration of action and must be administered two to three times per week.
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
Testosterone was first isolated and synthesized in 1935. [128] Shortly thereafter, in 1937, testosterone first became commercially available as a pharmaceutical drug in the form of pellets and then in ester form for intramuscular injection as the relatively short-acting testosterone propionate.
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