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H2 antagonists, sometimes referred to as H2RAs[ 1] and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H 2 receptors of the parietal cells in the stomach. This decreases the production of stomach acid. H 2 antagonists can be used in the treatment of dyspepsia, peptic ulcers and ...
Famotidine. Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [ 4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [ 4] It is taken by mouth or by injection into a vein. [ 4]
H2 blockers, short for histamine-2 blockers, are effective at blocking the production of stomach acid, so there’s less created during digestion. “They bind to the histamine-2 receptor in the ...
Cimetidine is a histamine type 2 blocker, which also binds to the androgen receptor to inhibit its function." However, this antiandrogen activity of cimetidine is weak, and the clinical benefit of its use in women with hirsutism is minimal. Thus, this drug is not recommended for the treatment of hyperandrogenism.
The proton pump is the terminal stage in gastric acid secretion, being directly responsible for secreting H + ions into the gastric lumen, making it an ideal target for inhibiting acid secretion. [ citation needed ] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective than receptor ...
Stomach acid or food coming back up into the esophagus (regurgitation) ... further testing and a trial of medications such as H2 blockers or PPIs may be necessary. Complications.
Proton-pump inhibitors. Proton-pump inhibitors ( PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available. The group followed and has largely superseded another group of pharmaceuticals with similar effects, but a different ...
H2 antagonists (H2 blockers) are used to reduce stomach acid production and treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. [ 3 ] H 3 receptor H3 Receptors: These receptors are predominantly located in the central nervous system (CNS), particularly in regions associated with neurotransmitter release and modulation.
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