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  2. Neuropathic pain - Wikipedia

    en.wikipedia.org/wiki/Neuropathic_pain

    Neuropathic pain has profound physiological effects on the brain which can manifest as psychological disorders. Rodent models where the social effects of chronic pain can be isolated from other factors suggest that induction of chronic pain can cause anxio-depressive symptoms and that particular circuits in the brain have a direct connection.

  3. Diffuse noxious inhibitory control - Wikipedia

    en.wikipedia.org/wiki/Diffuse_noxious_inhibitory...

    The DNIC model is used frequently to quantify the central pain sensitization in chronic pain patients. DNIC inefficiency (or lower DNIC) has been implicated as a risk factor for development of chronic pain and pain syndromes. [4] Chronic pain disorders such as temporomandibular disorder [5] and fibromyalgia [6] have been associated with DNIC ...

  4. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    Afferent pain-receptive nerves, those that bring signals to the brain, comprise at least two kinds of fibers - a fast, relatively thick, myelinated "Aδ" fiber that carries messages quickly with intense pain, and a small, unmyelinated, slow "C" fiber that carries the longer-term throbbing and chronic pain. Large-diameter Aβ fibers are ...

  5. Wide dynamic range neuron - Wikipedia

    en.wikipedia.org/wiki/Wide_dynamic_range_neuron

    Another type of pain, known as neuropathic pain, is caused by a direct problem or disease that affects the nerves in the central nervous system. [11] The sensory pathways the WDR neurons can play a role in. A subset of this neuropathic pain, known as chronic neuropathic pain, is characterized by its long lasting and high pain intensity.

  6. List of chronic pain syndromes - Wikipedia

    en.wikipedia.org/wiki/List_of_chronic_pain_syndromes

    Explanatory model of chronic pain. Chronic pain is defined as reoccurring or persistent pain lasting more than 3 months. [1] The International Association for the Study of Pain (IASP) defines pain as "An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage". [2]

  7. Cortical stimulation mapping - Wikipedia

    en.wikipedia.org/wiki/Cortical_stimulation_mapping

    Cortical stimulation identifies which regions of the brain are vital for certain functions, thereby allowing a 'map' to be made which can be used to decide if brain areas are safe to remove. Cortical stimulation mapping led to the development of a homunculus for the motor and sensory cortices, which is a diagram showing the brain's connections ...

  8. List of neurological conditions and disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_neurological...

    This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...

  9. Chronic pain - Wikipedia

    en.wikipedia.org/wiki/Chronic_pain

    The International Association for the Study of Pain (IASP) defines chronic pain as a general pain without biological value that sometimes continues even after the healing of the affected area; [8] [9] a type of pain that cannot be classified as acute pain [b] and lasts longer than expected to heal, or typically, pain that has been experienced on most days or daily for the past six months, is ...