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Pyridoxine/doxylamine, sold under the brand name Diclectin among others, is a combination of pyridoxine hydrochloride (vitamin B 6) and doxylamine succinate.It is generally used for nausea and vomiting of pregnancy (morning sickness); even though its efficacy has not been proven and subsequent research has led to the removal of recommendations in medical journals.
Metopimazine is an approved prescription drug in France under the brand name Vogalene® [8] that has been used for the treatment of nausea and vomiting. [9] Vogalene® is available under different forms, including 15 mg capsules, 7.5 mg orally disintegrating tablets, 5 mg suppository, 0.1% oral liquid, and a 10 mg/mL intravenous (IV) solution approved for the prevention of chemotherapy-induced ...
Doxylamine alone is available over-the-counter, whereas doxylamine in combination with pyridoxine is a prescription-only medication. [22] Doxylamine is also available in over-the-counter nighttime cold medicine products such as NyQuil Cold & Flu (contains acetaminophen , doxylamine succinate 6.25 to 12.5 mg, and dextromethorphan hydrobromide ...
The medication provides relief from nausea by blocking D 2 receptors in the chemoreceptor trigger zone and from gastrointestinal symptoms by blocking D 2 receptors in the gut. [ 20 ] [ 2 ] It blocks D 2 receptors in the lactotrophs of the anterior pituitary gland increasing release of prolactin which in turn increases lactation .
Morning sickness, also called nausea and vomiting of pregnancy (NVP), is a symptom of pregnancy that involves nausea or vomiting. [1] Despite the name, nausea or vomiting can occur at any time during the day. [2] Typically the symptoms occur between the 4th and 16th weeks of pregnancy. [2] About 10% of women still have symptoms after the 20th ...
But some pregnant women experience extreme vomiting and nausea, known as HG, which often needs hospital treatment. According to the NHS, HG affects about one to three in every 100 pregnant women.
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