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  2. Early Life Stage test - Wikipedia

    en.wikipedia.org/wiki/Early_Life_Stage_test

    An early life stage (ELS) test is a chronic toxicity test using sensitive early life stages like embryos or larvae to predict the effects of toxicants on organisms. [1] ELS tests were developed to be quicker and more cost-efficient than full life-cycle tests, taking on average 1–5 months to complete compared to 6–12 months for a life-cycle test.

  3. Developmental toxicity - Wikipedia

    en.wikipedia.org/wiki/Developmental_toxicity

    Developmental toxicity is any developmental malformation that is caused by the toxicity of a chemical or pathogen. It is the structural or functional alteration, reversible or irreversible, which interferes with homeostasis , normal growth , differentiation , development or behavior.

  4. Environmental toxicants and fetal development - Wikipedia

    en.wikipedia.org/wiki/Environmental_toxicants...

    Intrauterine exposure to dioxins and dioxin-like compounds have been associated with subtle developmental changes on the fetus. Effects on the child later in life include changes in liver function, thyroid hormone levels, white blood cell levels, and decreased performance in tests of learning and intelligence. [21]

  5. Teratology - Wikipedia

    en.wikipedia.org/wiki/Teratology

    Teratology is the study of abnormalities of physiological development in organisms during their life span. It is a sub-discipline in medical genetics which focuses on the classification of congenital abnormalities in dysmorphology caused by teratogens.

  6. Lowest-observed-adverse-effect level - Wikipedia

    en.wikipedia.org/wiki/Lowest-observed-adverse...

    The lowest-observed-adverse-effect level (LOAEL), or the lowest-observed-adverse-effect concentration (LOAEC), is the lowest concentration or amount of a substance found by experiment or observation that causes an adverse alteration of morphology, function, capacity, growth, development, or lifespan of a target organism distinguished from normal organisms of the same species under defined ...

  7. Toxicology testing - Wikipedia

    en.wikipedia.org/wiki/Toxicology_testing

    U.S. Army Public Health Center Toxicology Lab technician assessing samples. Toxicology testing, also known as safety assessment, or toxicity testing, is the process of determining the degree to which a substance of interest negatively impacts the normal biological functions of an organism, given a certain exposure duration, route of exposure, and substance concentration.

  8. Ohio Department of Health - Wikipedia

    en.wikipedia.org/wiki/Ohio_Department_of_Health

    The Ohio Department of Health (ODH) is the administrative department of the Ohio state government [1] responsible for coordinating activities for child and family health services, children with medical handicaps, early intervention services, nutrition services, and community health services; ensure the quality of both public health and health care delivery systems; and evaluates health status ...

  9. ISO 10993 - Wikipedia

    en.wikipedia.org/wiki/ISO_10993

    Part 1: Evaluation and testing within a risk management process Part 2: Animal welfare requirements Part 3: Tests for genotoxicity, carcinogenicity and reproductive toxicity Part 4: Selection of tests for interactions with blood Part 5: Tests for in vitro cytotoxicity. Part 6: Tests for local effects after implantation