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X-linked recessive inheritance. X-linked recessive inheritance is a mode of inheritance in which a mutation in a gene on the X chromosome causes the phenotype to be always expressed in males (who are necessarily hemizygous for the gene mutation because they have one X and one Y chromosome) and in females who are homozygous for the gene mutation, see zygosity.
In addition, alopecia areata shares genetic risk factors with other autoimmune diseases, including rheumatoid arthritis, type 1 diabetes, and celiac disease. [8] It may be the only manifestation of celiac disease. [27] [28] Endogenous retinoids metabolic defect is a key part of the pathogenesis of the alopecia areata. [29]
A–T can cause features of early aging such as premature graying of the hair. It can also cause vitiligo (an auto-immune disease causing loss of skin pigment resulting in a blotchy "bleach-splashed" look), and warts which can be extensive and recalcitrant to treatment. A small number of people develop a chronic inflammatory skin disease ...
Necrotizing fasciitis (NF), also known as flesh-eating disease, is a bacterial infection that results in the death of parts of the body's soft tissue. [3] It is a severe disease of sudden onset that spreads rapidly. [3] Symptoms usually include red or purple skin in the affected area, severe pain, fever, and vomiting. [3]
Myiasis (/ m aɪ. ˈ aɪ. ə. s ə s / my-EYE-ə-səss [1]), also known as flystrike or fly strike, is the parasitic infestation of the body of a live animal by fly larvae that grow inside the host while feeding on its tissue.
The usual signs and symptoms of pregnancy do not significantly interfere with activities of daily living or pose a health-threat to the mother or baby. However, pregnancy complications can cause other more severe symptoms, such as those associated with anemia. Common signs and symptoms of pregnancy include: Tiredness; Morning sickness; Constipation
Cri du chat syndrome is a rare genetic disorder due to a partial chromosome deletion on chromosome 5. [1] Its name is a French term ("cat-cry" or "call of the cat") referring to the characteristic cat-like cry of affected children (sound sample ). [2]
Physical arousal caused by PGAD can be very intense and persist for extended periods, days, weeks or years at a time. [3] [4] Symptoms may include pressure, pain, vibrating, pleasure, irritation, clitoral or penile [5] tingling, throbbing, vaginal congestion, vaginal contractions, penile spasms, arousal, clitoral or penile erections, and prolonged spontaneous orgasms. [3]