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  2. McCune–Albright syndrome - Wikipedia

    en.wikipedia.org/wiki/McCune–Albright_syndrome

    Medical genetics. Named after. Donovan James McCune. Fuller Albright. McCune–Albright syndrome is a complex genetic disorder affecting the bone, skin and endocrine systems. It is a mosaic disease arising from somatic activating mutations in GNAS, which encodes the alpha-subunit of the G s heterotrimeric G protein. [ 1]

  3. Hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Hyperpigmentation

    Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair. The process of melanin synthesis (melanogenesis ...

  4. Schamberg disease - Wikipedia

    en.wikipedia.org/wiki/Schamberg_disease

    Schamberg's disease, or progressive pigmented purpuric dermatosis, is a chronic discoloration of the skin which usually affects the legs and often spreads slowly. This disease is more common in males and may occur at any age from childhood onward. This condition is observed worldwide and has nothing to do with race or ethnic background.

  5. Noonan syndrome with multiple lentigines - Wikipedia

    en.wikipedia.org/wiki/Noonan_syndrome_with...

    Noonan syndrome with multiple lentigines ( NSML) which is part of a group called Ras / MAPK pathway syndromes, [2] is a rare autosomal dominant, [3] multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene ( PTPN11 ). The disease is a complex of features, mostly involving the skin, skeletal and ...

  6. List of skin conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_skin_conditions

    The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]

  7. How to Get Rid of Dark Spots on Your Face, According to ... - AOL

    www.aol.com/rid-dark-spots-face-according...

    Fade dark spots with proven solutions from top experts including dermatologists and aestheticians. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290 ...

  8. How to get rid of sun spots on your face and prevent ... - AOL

    www.aol.com/news/rid-sun-spots-face-prevent...

    The above ingredients can be incorporated into a daily skin care routine to help reduce the look of sun spots on your face over time, Hu says. But a dermatologist can offer other treatments to ...

  9. Freckle - Wikipedia

    en.wikipedia.org/wiki/Freckle

    Freckle. Freckles are clusters of concentrated melaninized cells which are most easily visible on people with a fair complexion. Freckles do not have an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules ( melanosomes) changing the coloration of the outer skin cells ...