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  2. Calcifediol - Wikipedia

    en.wikipedia.org/wiki/Calcifediol

    Calcifediol, also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D3 (abbreviated 25 (OH)D3), [1] is a form of vitamin D produced in the liver by hydroxylation of vitamin D 3 (cholecalciferol) by the enzyme vitamin D 25-hydroxylase. [3][4][5] Calcifediol can be further hydroxylated by the enzyme 25 (OH)D-1α-hydroxylase ...

  3. Vitamin D deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_deficiency

    Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body. [1][7][2] One nanogram per millilitre (1 ng/mL) is equivalent to 2.5 nanomoles per litre (2.5 nmol/L). Severe deficiency: <12 ng/mL = <30 nmol/L[2] Deficiency ...

  4. 24,25-Dihydroxycholecalciferol - Wikipedia

    en.wikipedia.org/wiki/24,25-Dihydroxycholecalciferol

    24,25-Dihydroxycholecalciferol, also known as 24,25-dihydroxyvitamin D3 and (24R)-hydroxycalcidiol (abbreviated as 24 (R),25- (OH)2D3), [1] is a compound which is closely related to 1,25-dihydroxyvitamin D 3, the active form of vitamin D 3. Like vitamin D 3 itself and calcifediol (25-hydroxyvitamin D 3), it is inactive as a hormone both in ...

  5. Vitamin D - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D

    A diet insufficient in vitamin D, combined with inadequate sunlight exposure, can lead to vitamin D deficiency, which is defined as a blood 25-hydroxyvitamin D or 25(OH)D level below 12 ng/mL (30 nmol/liter). Vitamin D insufficiency, on the other hand, is characterized by a blood 25(OH)D level between 12–20 ng/mL (30–50 nmol/liter).

  6. Cholecalciferol - Wikipedia

    en.wikipedia.org/wiki/Cholecalciferol

    Cholecalciferol is a form of vitamin D which is naturally synthesized in skin and functions as a pro-hormone, being converted to calcitriol. This is important for maintaining calcium levels and promoting bone health and development. [4] As a medication, cholecalciferol may be taken as a dietary supplement to prevent or to treat vitamin D ...

  7. Calcitriol - Wikipedia

    en.wikipedia.org/wiki/Calcitriol

    Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [8][9][10] It is also known as 1,25-dihydroxycholecalciferol. It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]

  8. Vitamin D3 24-hydroxylase - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D3_24-hydroxylase

    Vitamin D3 24-hydroxylase (EC 1.14.15.16, CYP24A1) is an enzyme with systematic name calcitriol,NADPH:oxygen oxidoreductase (24-hydroxylating).

  9. CYP24A1 - Wikipedia

    en.wikipedia.org/wiki/CYP24A1

    Cytochrome P450 family 24 subfamily A member 1 (abbreviated CYP24A1) is a member of the cytochrome P450 superfamily of enzymes encoded by the CYP24A1 gene. It is a mitochondrial monooxygenase which catalyzes reactions including 24-hydroxylation of calcitriol (1,25-dihydroxyvitamin D 3). [5] It has also been identified as vitamin D3 24-hydroxylase.

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