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  2. Effects of cannabis - Wikipedia

    en.wikipedia.org/wiki/Effects_of_cannabis

    Cannabis use disorder is defined in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders as a condition requiring treatment. [107] Several drugs have been investigated in an attempt to ameliorate the symptoms of stopping cannabis use. Such drugs include bupropion, divalproex, nefazodone, lofexidine, and dronabinol.

  3. Long-term effects of cannabis - Wikipedia

    en.wikipedia.org/wiki/Long-term_effects_of_cannabis

    Medical evidence strongly suggests that the long-term use of cannabis by people who begin use at an early age display a higher tendency towards mental health problems and other physical and development disorders, although a causal link could not be proven by the available data. [27] The risks appear to be most acute in adolescent users. [27]

  4. Nicotine dependence - Wikipedia

    en.wikipedia.org/wiki/Nicotine_dependence

    A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [21]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [9]

  5. Nicotine - Wikipedia

    en.wikipedia.org/wiki/Nicotine

    Nicotine is a hygroscopic, colorless to yellow-brown, oily liquid, that is readily soluble in alcohol, ether or light petroleum. It is miscible with water in its neutral amine base form between 60 °C and 210 °C. It is a dibasic nitrogenous base, having K b1 =1×10 −6, K b2 =1×10 −11. [ 163 ]

  6. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    Substance abuse, also known as drug abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a form of substance-related disorder. Differing definitions of drug abuse are used in public health, medical, and criminal justice contexts. In some cases, criminal or anti-social behavior occurs when the ...

  7. Cannabinoid hyperemesis syndrome - Wikipedia

    en.wikipedia.org/wiki/Cannabinoid_hyperemesis...

    Cannabinoid hyperemesis syndrome. Cannabinoid hyperemesis syndrome (CHS) is recurrent nausea, vomiting, and cramping abdominal pain that can occur due to prolonged, high-dose cannabis use. [ 4 ][ 5 ] Complications are related to persistent vomiting and dehydration which may lead to kidney failure and electrolyte problems. [ 2 ]

  8. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    Substance use disorder (SUD) is the persistent use of drugs despite the substantial harm and adverse consequences to one's own self and others, as a result of their use. [7] [8] In perspective, the effects of the wrong use of substances that are capable of causing harm to the user or others, have been extensively described in different studies using a variety of terms such as substance use ...

  9. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    These specifiers are determined by the number of diagnostic criteria present in a given case. In the DSM-5, the term drug addiction is synonymous with severe substance use disorder. [18] [24] The DSM-5 introduced a new diagnostic category for behavioral addictions. Problem gambling is the only condition included in this category in the fifth ...